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1

PI3K class IB controls the cell cycle checkpoint promoting cell proliferation in hepatocellular carcinoma

Francesco Dituri, Antonio Mazzocca, Luigi Lupo, Charlotte E. Edling, Amalia Azzariti, Salvatore Antonaci, Marco Falasca, Gianluigi Giannelli

Journal:

International Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 1.92 MB

english, 2012

2

PI3K Functions in Cancer Progression, Anticancer Immunity and Immune Evasion by Tumors

Dituri, Francesco, Mazzocca, Antonio, Giannelli, Gianluigi, Antonaci, Salvatore

Journal:

Clinical & Developmental Immunology

Year:

2011

Language:

english

File:

PDF, 264 KB

english, 2011

3

The rationale for targeting TGF-β in chronic liver diseases

Giannelli, Gianluigi, Mikulits, Wolfgang, Dooley, Steven, Fabregat, Isabel, Moustakas, Aristidis, ten Dijke, Peter, Portincasa, Piero, Winter, Peter, Janssen, Richard, Leporatti, Stefano, Herrera, Bla

Journal:

European Journal of Clinical Investigation

Year:

2016

Language:

english

File:

PDF, 498 KB

english, 2016

4

Basiliximab Versus Steroids in Double Therapy Immunosuppression in Liver Transplantation: A Prospective Randomized Clinical Trial

Lupo, Luigi, Panzera, Piercarmine, Tandoi, Francesco, Carbotta, Giuseppe, Giannelli, Gianluigi, Santantonio, Teresa, Rendina, Maria, Gentile, Antonietta, Memeo, Vincenzo

Journal:

Transplantation Journal

Year:

2008

Language:

english

File:

PDF, 676 KB

english, 2008

5

TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer

Caja, Laia, Dituri, Francesco, Mancarella, Serena, Caballero-Diaz, Daniel, Moustakas, Aristidis, Giannelli, Gianluigi, Fabregat, Isabel

Journal:

International Journal of Molecular Sciences

Year:

2018

Language:

english

File:

PDF, 1.29 MB

english, 2018

6

Signaling networks in cholangiocarcinoma: molecular pathogenesis, targeted therapies and drug resistance

Fouassier, Laura, Marzioni, Marco, Afonso, Marta B., Dooley, Steven, Gaston, Kevin, Giannelli, Gianluigi, Rodrigues, Cecilia M. P., Lozano, Elisa, Mancarella, Serena, Segatto, Oreste, Vaquero, Javier,

Journal:

Liver International

Year:

2019

Language:

english

File:

PDF, 1.00 MB

english, 2019

7

Development of disease-modifying drugs for frontotemporal dementia spectrum disorders

Panza, Francesco, Lozupone, Madia, Seripa, Davide, Daniele, Antonio, Watling, Mark, Giannelli, Gianluigi, Imbimbo, Bruno P.

Journal:

Nature Reviews Neurology (formerly Nature Clinical Practice Neurology)

Year:

2020

Language:

english

File:

PDF, 2.09 MB

english, 2020

8

Case of multiple myeloma mimicking an infectious disease with fever, intrahepatic cholestasis, renal failure, and pulmonary insufficiency

Francesco S. Vella, Barbara Simone, Gianluigi Giannelli, MariaTeresa Pesolo, Giuseppe Ingravallo, Antonia Gentile, Salvatore Antonaci

Journal:

American Journal of Hematology

Year:

2003

Language:

english

File:

PDF, 189 KB

english, 2003

9

Psoriatic lesions in patients with chronic liver disease are distinct from psoriasis vulgaris lesions, as judged on basis of integrin adhesion receptors

Gianluigi Giannelli, Paola Savoia, Oronzo Schiraldi, Mario Lospalluti, Michele De Luca, Dr. Pier Carlo Marchisio, Vito Quaranta

Journal:

Year:

1994

Language:

english

File:

PDF, 1.23 MB

english, 1994

10

Laminin-5 stimulates hepatocellular carcinoma growth through a different function of α6β4 and α3β1 integrins

Carlo Bergamini, Concetta Sgarra, Paolo Trerotoli, Luigi Lupo, Amalia Azzariti, Salvatore Antonaci, Gianluigi Giannelli

Journal:

Year:

2007

Language:

english

File:

PDF, 1.45 MB

english, 2007

11

Blocking transforming growth factor–beta up-regulates E-cadherin and reduces migration and invasion of hepatocellular carcinoma cells

Emilia Fransvea, Umberto Angelotti, Salvatore Antonaci, Gianluigi Giannelli

Journal:

Year:

2008

Language:

english

File:

PDF, 3.18 MB

english, 2008

12

Targeting transforming growth factor (TGF)-βRI inhibits activation of β1 integrin and blocks vascular invasion in hepatocellular carcinoma

Emilia Fransvea, Antonio Mazzocca, Salvatore Antonaci, Gianluigi Giannelli

Journal:

Year:

2009

Language:

english

File:

PDF, 2.33 MB

english, 2009

13

Inhibition of transforming growth factor β receptor I kinase blocks hepatocellular carcinoma growth through neo-angiogenesis regulation

Antonio Mazzocca, Emilia Fransvea, Gabriela Lavezzari, Salvatore Antonaci, Gianluigi Giannelli

Journal:

Year:

2009

Language:

english

File:

PDF, 3.35 MB

english, 2009

14

Down-regulation of connective tissue growth factor by inhibition of transforming growth factor β blocks the tumor–stroma cross-talk and tumor progression in hepatocellular carcinoma

Antonio Mazzocca, Emilia Fransvea, Francesco Dituri, Luigi Lupo, Salvatore Antonaci, Gianluigi Giannelli

Journal:

Year:

2010

Language:

english

File:

PDF, 5.02 MB

english, 2010

15

The epithelial-mesenchymal transition: Fact or fiction in cancer?

Gianluigi Giannelli

Journal:

Year:

2009

Language:

english

File:

PDF, 303 KB

english, 2009

16

Reply:

Antonio Mazzocca, Salvatore Antonaci, Gianluigi Giannelli

Journal:

Year:

2009

Language:

english

File:

PDF, 39 KB

english, 2009

17

Tumor-secreted lysophostatidic acid accelerates hepatocellular carcinoma progression by promoting differentiation of peritumoral fibroblasts in myofibroblasts

Antonio Mazzocca, Francesco Dituri, Luigi Lupo, Michele Quaranta, Salvatore Antonaci, Gianluigi Giannelli

Journal:

Year:

2011

Language:

english

File:

PDF, 980 KB

english, 2011

18

Clinical role of MMP-2/TIMP-2 imbalance in hepatocellular carcinoma

Gianluigi Giannelli, Carlo Bergamini, Felice Marinosci, Emilia Fransvea, Michele Quaranta, Luigi Lupo, Oronzo Schiraldi, Salvatore Antonaci

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 2.25 MB

english, 2002

19

Proteolytic imbalance is reversed after therapeutic surgery in breast cancer patients

Gianluigi Giannelli, Roberta Erriquez, Emilia Fransvea, Antonella Daniele, Paolo Trerotoli, Francesco Schittulli, Maria Grano, Michele Quaranta, Salvatore Antonaci

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 158 KB

english, 2004

20

Clinical role of tissue and serum levels of SCCA antigen in hepatocellular carcinoma

Gianluigi Giannelli, Felice Marinosci, Concetta Sgarra, Luigi Lupo, Pietro Dentico, Salvatore Antonaci

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 267 KB

english, 2005

21

MMP and TIMP assay in cancer: Biological and clinical significance

Gianluigi Giannelli, Salvatore Antonaci

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 42 KB

english, 2005

22

SCCA antigen combined with alpha-fetoprotein as serologic markers of HCC

Gianluigi Giannelli, Felice Marinosci, Paolo Trerotoli, Anna Volpe, Michele Quaranta, Pietro Dentico, Salvatore Antonaci

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 77 KB

english, 2005

23

Occurrence of portal vein tumor thrombus in hepatocellular carcinoma affects prognosis and survival.: A retrospective clinical study of 150 cases

Gianluigi Giannelli, Francesca Pierri, Paolo Trerotoli, Felice Marinosci, Gabriella Serio, Oronzo Schiraldi, Salvatore Antonaci

Journal:

Hepatology Research

Year:

2002

Language:

english

File:

PDF, 118 KB

english, 2002

24

Gelatinase expression at positive patch test reactions

Gianluigi Giannelli, Caterina Foti, Felice Marinosci, Domenico Bonamonte, Salvatore Antonaci, Giovanni Angelini

Journal:

Contact Dermatitis

Year:

2002

Language:

english

File:

PDF, 102 KB

english, 2002

25

Complete response for advanced liver cancer during sorafenib therapy: Case Report

Rodolfo Sacco, Irene Bargellini, Giannelli Gianluigi, Marco Bertini, Elena Bozzi, Emanuele Altomare, Valentina Battaglia, Antonio Romano, Michele Bertoni, Alfonso Capria, Giampaolo Bresci, Carlo Barto

Journal:

BMC Gastroenterology

Year:

2011

Language:

english

File:

PDF, 1.32 MB

english, 2011

26

Kinase activation profile associated with TGF-β-dependent migration of HCC cells: a preclinical study

Emilia Fransvea, Antonio Mazzocca, Angela Santamato, Amalia Azzariti, Salvatore Antonaci, Gianluigi Giannelli

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 388 KB

english, 2011

27

Human Hepatocellular Carcinoma (HCC) Cells Require Both α3β1 Integrin and Matrix Metalloproteinases Activity for Migration and Invasion

Giannelli, Gianluigi, Bergamini, Carlo, Fransvea, Emilia, Marinosci, Felice, Quaranta, Vito, Antonaci, Salvatore

Journal:

Laboratory Investigation

Year:

2001

Language:

english

File:

PDF, 9.00 MB

english, 2001

28

Biological and clinical relevance of Laminin-5 in cancer

Gianluigi Giannelli, Salvatore Antonaci

Journal:

Clinical and Experimental Metastasis

Year:

2000

Language:

english

File:

PDF, 124 KB

english, 2000

29

Role of the α3β1 and α6β4 integrins in tumor invasion

Gianluigi Giannelli, Simonetta Astigiano, Salvatore Antonaci, Monica Morini, Ottavia Barbieri, Douglas M. Noonan, Adriana Albini

Journal:

Clinical and Experimental Metastasis

Year:

2002

Language:

english

File:

PDF, 127 KB

english, 2002

30

Polyelectrolyte Capsules as Carriers for Growth Factor Inhibitor Delivery to Hepatocellular Carcinoma

Francesca Baldassarre, Viviana Vergaro, Flavia Scarlino, Flavia De Santis, Giovanna Lucarelli, Antonio della Torre, Giuseppe Ciccarella, Ross Rinaldi, Gianluigi Giannelli, Stefano Leporatti

Journal:

Macromolecular Bioscience

Year:

2012

Language:

english

File:

PDF, 686 KB

english, 2012

31

Fate of antibody to interferon (IFN) in chronic hepatitis C patients treated with recombinant IFN alpha 2 and retreated with lymphoblastoid IFN alpha

Guido Antonelli, Gianluigi Giannelli, Maurizio Currenti, Eleonora Simeoni, Michele Milella, Oronzo Schiraldi, Ferdinando Dianzani

Journal:

International Hepatology Communications

Year:

1995

Language:

english

File:

PDF, 392 KB

english, 1995

32

Drug-loaded polyelectrolyte microcapsules for sustained targeting of cancer cells

Viviana Vergaro, Flavia Scarlino, Claudia Bellomo, Rosaria Rinaldi, Daniele Vergara, Michele Maffia, Francesca Baldassarre, Gianluigi Giannelli, Xingcai Zhang, Yuri M. Lvov, Stefano Leporatti

Journal:

Advanced Drug Delivery Reviews

Year:

2011

Language:

english

File:

PDF, 1.82 MB

english, 2011

33

Inhibiting TGF-β signaling in hepatocellular carcinoma

Gianluigi Giannelli, Antonio Mazzocca, Emilia Fransvea, Michael Lahn, Salvatore Antonaci

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

2011

Language:

english

File:

PDF, 702 KB

english, 2011

34

Involvement of ADAMs in tumorigenesis and progression of hepatocellular carcinoma: Is it merely fortuitous or a real pathogenic link?

Antonio Mazzocca, Gianluigi Giannelli, Salvatore Antonaci

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

2010

Language:

english

File:

PDF, 1.05 MB

english, 2010

35

ZD6474 inhibits proliferation and invasion of human hepatocellular carcinoma cells

Gianluigi Giannelli, Amalia Azzariti, Concetta Sgarra, Letizia Porcelli, Salvatore Antonaci, Angelo Paradiso

Journal:

Biochemical Pharmacology

Year:

2006

Language:

english

File:

PDF, 302 KB

english, 2006

36

AFP, PIVKAII, GP3, SCCA-1 and follisatin as surveillance biomarkers for hepatocellular cancer in non-alcoholic and alcoholic fatty liver disease

Gary Beale, Dipankar Chattopadhyay, Joe Gray, Stephen Stewart, Mark Hudson, Christopher Day, Paolo Trerotoli, Gianluigi Giannelli, Derek Manas, Helen Reeves

Journal:

Year:

2008

Language:

english

File:

PDF, 358 KB

english, 2008

37

Gelatinase Levels in Male and Female Breast Cancer

Gianluigi Giannelli, Emilia Fransvea, Felice Marinosci, Carlo Bergamini, Antonella Daniele, Silvia Colucci, Angelo Paradiso, Michele Quaranta, Salvatore Antonaci

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 259 KB

english, 2002

38

EGFR and VEGFR as potential target for biological therapies in HCC cells

Gianluigi Giannelli, Concetta Sgarra, Letizia Porcelli, Amalia Azzariti, Salvatore Antonaci, Angelo Paradiso

Journal:

Year:

2008

Language:

english

File:

PDF, 282 KB

english, 2008

39

Clinical validation of combined serological biomarkers for improved hepatocellular carcinoma diagnosis in 961 patients

Gianluigi Giannelli, Emilia Fransvea, Paolo Trerotoli, Michel Beaugrand, Felice Marinosci, Luigi Lupo, Gisele Nkontchou, Pietro Dentico, Salvatore Antonaci

Journal:

Clinica Chimica Acta

Year:

2007

Language:

english

File:

PDF, 348 KB

english, 2007

40

Glaucoma in primary amyloidosis: a fortuitous or causative association?

Francesco S Vella, Barbara Simone, Gianluigi Giannelli, Dario Sisto, Carlo Sborgia, Salvatore Antonaci

Journal:

The American Journal of Medicine

Year:

2002

Language:

english

File:

PDF, 108 KB

english, 2002

41

Transforming Growth Factor-β1 Triggers Hepatocellular Carcinoma Invasiveness via α3β1 Integrin

Gianluigi Giannelli, Emilia Fransvea, Felice Marinosci, Carlo Bergamini, Silvia Colucci, Oronzo Schiraldi, Salvatore Antonaci

Journal:

The American Journal of Pathology

Year:

2002

Language:

english

File:

PDF, 1.30 MB

english, 2002

42

Expression of Matrix Metalloprotease-2-Cleaved Laminin-5 in Breast Remodeling Stimulated by Sex Steroids

Gianluigi Giannelli, Ambra Pozzi, William G. Stetler-Stevenson, Humphrey A. Gardner, Vito Quaranta

Journal:

The American Journal of Pathology

Year:

1999

Language:

english

File:

PDF, 1.24 MB

english, 1999

43

Reply

Mazzocca, Antonio, Giannelli, Gianluigi

Journal:

Year:

2013

Language:

english

File:

PDF, 349 KB

english, 2013

44

Tissue expression of Squamous Cellular Carcinoma Antigen (SCCA) is inversely correlated to tumor size in HCC

Paolo Trerotoli, Emilia Fransvea, Umberto Angelotti, Giovanni Antonaci, Luigi Lupo, Antonio Mazzocca, Anita Mangia, Salvatore Antonaci, Gianluigi Giannelli

Journal:

Molecular Cancer

Year:

2009

Language:

english

File:

PDF, 1.76 MB

english, 2009

45

Automatic transwell assay by an EIS cell chip to monitor cell migration

Primiceri, Elisabetta, Chiriacò, Maria Serena, Dioguardi, Francesca, Monteduro, Anna Grazia, D'Amone, Eliana, Rinaldi, Ross, Giannelli, Gianluigi, Maruccio, Giuseppe

Journal:

Year:

2011

Language:

english

File:

PDF, 281 KB

english, 2011

46

Clinical Role of Serum and Tissue Matrix Metalloprotease-9 Expression in Chronic HCV Patients Treated with Pegylated IFN-α2b and Ribavirin

Marinosci, Felice, Bergamini, Carlo, Fransvea, Emilia, Napoli, Nicola, Maurel, Patrick, Dentico, Pietro, Antonaci, Salvatore, Giannelli, Gianluigi

Journal:

Journal of Interferon & Cytokine Research

Year:

2005

Language:

english

File:

PDF, 349 KB

english, 2005

47

Interplay between cancer cells, macrophages and natural killer cells may actually decide the outcome of therapy with sorafenib

Tomuleasa, Ciprian, Giannelli, Gianluigi, Cucuianu, Andrei, Aldea, Mihaela, Paradiso, Angelo, Berindan-Neagoe, Ioana

Journal:

Year:

2014

Language:

english

File:

PDF, 270 KB

english, 2014

48

Role of Cell Surface Metalloprotease MT1-MMP in Epithelial Cell Migration over Laminin-5

Naohiko Koshikawa, Gianluigi Giannelli, Vincenzo Cirulli, Kaoru Miyazaki and Vito Quaranta

Journal:

The Journal of Cell Biology

Year:

2000

Language:

english

File:

PDF, 2.68 MB

english, 2000

49

Circulating TGF-β1-related biomarkers in patients with hepatocellular carcinoma and their association with HCC staging scores

Dituri, Francesco, Serio, Gabriella, Filannino, Doriana, Mascolo, Antonella, Sacco, Rodolfo, Villa, Erica, Giannelli, Gianluigi

Journal:

Year:

2014

Language:

english

File:

PDF, 1.49 MB

english, 2014

50

LY2157299-loaded carriers inhibiting wound healing in hepatocellular carcinoma

Hanafy, Nemany A., Nobile, Concetta, De Giorgi, Maria Luisa, Ran, Bhavna, Cao, Yuan, Giannelli, Gianluigi, Leporatti, Stefano

Journal:

Journal of Biotechnology

Year:

2014

Language:

english

File:

PDF, 67 KB

english, 2014